Sunday, November 21, 2010

The trippy world inside the cell

My friend Cathy sent me this video with this message:

"This is ballin' and I thought you'd enjoy it too. I'm not endorsing drug use of course, but......if you ever choose to do drugs, this is the kind of trippy stuff I imagine you'd have a blast with."

As you watch this, keep in mind that ALL OF THIS IS HAPPENING INSIDE YOU RIGHT NOW.
Fullscreen recommended. 




Now that we're being total nerds, I'm gonna go ahead and point out a few things that the video got wrong.

Did you notice how the necessary proteins seemed to float through the empty void and land directly on the spot they were needed? That's not what happens. In reality, the cell is completely and utterly packed with proteins and other molecules, with water filling in any available nook and cranny. And the only way complimentary molecules "find" each other is because they're jittering back and forth a zillion times a second. I think we can forgive the animators though: nobody wants to watch a quickly shivering glob of goop.

The second thing to remember is that the processes are not as smooth as they appear. In real molecular interactions, proteins don't always bind and stay put; they often screw up and unbind when they're not "supposed to". The end result comes about because of a net tendency of the molecule to, in this case, bind more often than unbind.

Finally, the clips are probably not showing these processes in real time. Most of these interactions occur at much faster rates.

If you want to read the article that went with the video, you can find it here.

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